DSM BioSolutions, DSM’s microbial fermentation CMO business unit, and PolyTherics Ltd. have entered into an agreement for the process development and manufacture of PolyTherics’ lead “biobetter” product, HiPEG IFN α-2a. Financial terms were not disclosed. PolyTherics applied its HiPEG site-specific PEGylation technology to interferon alpha to produce HiPEG IFN α-2a, which in a preclinical study showed eight-fold higher activity than a marketed PEGylated interferon in vitro, and a comparable h...